A string of failed drug trials for Alzheimer's has researchers questioning the reigning approach to battling the disease, which focuses on preventing amyloid buildup in the brain. Scientists have identified a molecular mechanism that could help explain how neurons begin to falter even before amyloid clumps appear. The culprit, they say, may be 'jumping genes' that lose their normal controls with age and start to disrupt the machinery that fuels brain cells.
'Jumping genes' may set the stage for brain cell death in Alzheimer's, other diseases
Science Daily - 8 Mar 2017 22:44
A string of failed drug trials for Alzheimer's has researchers questioning the reigning approach to battling the disease, which focuses on preventing amyloid buildup in the brain. Scientists have identified a molecular mechanism that could help explain how neurons begin to falter even before amyloid clumps appear. The culprit, they say, may be 'jumping genes' that lose their normal controls with age and start to disrupt the machinery that fuels brain cells.
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